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MLB playoff primer

THE Kansas City Royals are in the postseason for the first time since winning the World Series of Major League Baseball (MLB) in 2015, the Tigers are ending a playoff drought that started that same year, and the Baltimore Orioles have an eight-game postseason losing streak that began after beating Detroit in a 2014 series.

At least one of those three teams will be playing in the American League (AL) Division Series this weekend.

Baseball’s playoffs start Tuesday with four wild-card games — two in the AL and two in the National League (NL) — in a best-of-three round.

The sixth-seeded Tigers will visit the third-seeded Houston Astros, a playoff regular, in the day’s first game. The fifth-seeded Royals meet the fourth-seeded Orioles, a talented squad due for a postseason breakout, in the second game.

In the NL, the third-seeded Milwaukee Brewers host the sixth-seeded New York Mets, and the fourth-seeded Padres clash with the fifth-seeded Atlanta Braves in Southern California in the last game of the day. San Diego is the hottest team since the All-Star break with a 43-20 record.

The Braves and Mets both got into the field by splitting a doubleheader on Monday. That left the defending NL champion Arizona Diamondbacks as the odd team out.

Four teams get the first round off: The top-seeded Los Angeles Dodgers and second-seeded Philadelphia Phillies in the NL, and the top-seeded New York Yankees and second-seeded Cleveland Guardians in the AL.

Here is a look at the pairings:

TIGERS (86-76) AT ASTROS (88-73)
Detroit traded away right-hander Jack Flaherty, outfielder/first baseman Mark Canha and left-handed reliever Andrew Chafin at the trade deadline, then released infielder Gio Urshela a few weeks later due to its season seemingly going nowhere. But a stunning 31-11 run, combined with the collapse of the Minnesota Twins, led to the Tigers ending their long playoff drought.

Detroit has the probable AL Cy Young Award winner in left-hander Tarik Skubal (18-4, 2.39 ERA), but the rest of the rotation is shaky. Outfielder Riley Greene (.262 average, 24 homers, 74 RBIs) is the top position player, and manager A.J. Hinch has expertly mixed and matched his roster all season to find timely production.

The Astros are the seasoned postseason squad and are part of the playoffs for the eighth season in a row. They won the World Series in 2017 (the sign-stealing group) and 2022 and finished this regular season strong with 11 wins in 16 games. Left-hander Framber Valdez (15-7, 2.91) is the ace, while legendary right-hander Justin Verlander might not make the playoff roster against his former club.

Houston slugger Yordan Alvarez (.308-35-86) is one of the most powerful hitters in the sport, and infielders Jose Altuve (.295-20-65) and Alex Bregman (.260-26-75) have been the core of the franchise’s dynasty. The Astros failed to reach the 90-win mark over the course of a 162-game season for the first time since 2016. Houston went 4-2 against Detroit this season.

The winner faces… the Guardians (92-69), who were surprisingly potent in Stephen Vogt’s first season as manager. Jose Ramirez (.279-39-118) might be the most unsung six-time All-Star in the history of the sport, but he has just two homers in 32 postseason games.

ROYALS (86-76) AT ORIOLES (91-71)
One of the top players on Kansas City’s back-to-back World Series teams in 2014-15 is one of the top performers for this club. Catcher Salvador Perez (.271-27-104) was MVP of the 2015 Fall Classic and is the backbone of the organization. However, the club has a big-time star in shortstop Bobby Witt Jr. (.332-32-109 plus 31 steals), the AL batting champion who will finish near the top of AL MVP voting.

The Royals hadn’t even had a winning campaign since 2015 prior to this season. The free agent signing of right-hander Seth Lugo (16-9, 3.00), the possible Cy Young Award runner-up to Skubal, provided a big boost, as did the development of left-hander Cole Ragans (11-9, 3.14). Both pitchers made the AL All-Star team. — Reuters

SMB and Meralco kickstart EASL campaign against Korean and Macau side, respectively

Games on Wednesday
(Mall of Asia Arena)
6:10 p.m.  – San Miguel vs. Suwon KT Sonicboom
8:10 p.m.  – Meralco vs. Macau Black Bears

SAN MIGUEL BEER (SMB) and Meralco set out to fly the Philippine flag and give home fans a winning performance as they launch their campaigns in the East Asia Super League (EASL) on Wednesday at the MOA Arena.

The Beermen defend home ground and Filipino pride versus Korean side Suwon KT Sonicboom at 6:10 p.m. in their Group A clash, while the Bolts seek the same against the Macau Black Bears in Group B at 8:10 p.m. as the PBA champs feature in a double-header treat ushering in Season 2.

“It’s going to be one big show,” Banjo Albano, VP for business development and head of EASL Philippines said of the 2024-25 season kickoff during Tuesday’s Philippine Sportswriters Association (PSA) Forum.

“It’s the first time we’re doing it in Manila and we know how much Filipinos love the game of basketball. It’s not only an honor but more of an obligation to host the games here in Manila. We felt Manila is the best place to kick off the new season.”

Reigning Commissioner’s Cup holder San Miguel beefed up its talent-laden crew in the ongoing Governors’ Cup led by import Anosik and Gilas Pilipinas stalwarts June Mar Fajardo and CJ Perez with former NBA player Quincy Miller for the home-and-away EASL competition.

For its part, the reigning Philippine Cup kingpin Bolts tapped import DJ Kennedy and naturalized player Ange Kouame to complement the gang headlined by Allen Durham, Chris Newsome, Chris Banchero and Cliff Hodge.

“I think they’re looking to represent the Philippines the best way they can and compete for the championship this season,” noted Mr. Albano, who was joined by VP Head of Commercial and Broadcast Operations Adam Zecha in the session presented by San Miguel Corp., Philippine Sports Commission, Philippine Olympic Committee, MILO, Smart/PLDT, and ArenaPlus, the country’s 24/7 sports app.

An extra motivation for SMB and Meralco would be the hunger to win after suffering sorry losses in Monday’s PBA quarterfinals wars ahead of their EASL gigs. The Beermen blew a 25-point lead and lost to Converge, 112-114, to get dragged to a Game 4 in their Last-8 duel. The Bolts got it worse, yielding to Ginebra 106-113, and getting swept out of semis contention.

According to Mr. Zecha, Cignal TV is the broadcast partner of the EASL Season 2, allowing Filipino fans to catch the action on Cignal, One Sport, One Sport Plus, and Pilipinas Live. — Olmin Leyba

Major League Baseball legend Pete Rose dies at 83

PETE ROSE, the all-time Major League Baseball (MLB) leader in hits and games played who was banned for life for betting on baseball, died Monday. He was 83.

The medical examiner in Clark County, Nev., confirmed Rose’s death to ESPN after it was reported by TMZ and by ESPN baseball commentator Eduardo Perez, who said on “SportsCenter” that he had spoken with Rose’s son.

The engine of the “Big Red Machine” for a combined 19 years in Cincinnati, Rose helped the Reds win consecutive World Series in 1975 and 1976 before winning a third title with the Philadelphia Phillies in 1980. Rose won the 1973 National League MVP Award and the 1975 World Series MVP.

The man nicknamed “Charlie Hustle” also played for the Philadelphia Phillies (1979-84) and Montreal Expos (1984) in between stints with the Reds and went on to manage Cincinnati from 1984-89, the first three years as a player-manager.

“The Reds are heartbroken to learn of the passing of baseball legend Pete Rose,” the Reds posted on X, formerly Twitter, with a black and white photo of Rose in his playing days.

No one has surpassed Rose’s totals of 4,256 hits, 3,562 games or 14,053 at-bats. He ranks sixth all-time in runs (2,165). He was a lifetime .303 hitter with 160 home runs, 746 doubles and 1,314 RBIs.

Rose famously was not allowed into the Baseball Hall of Fame because of his lifetime ban, which was handed down in 1989. Shortly after, he pled guilty to two charges of tax evasion, as he had filed income tax returns that failed to include income from selling autographs and memorabilia.

He admitted to betting on baseball in 2004, insisting he never bet against the Reds, and for years he advocated for his ban to be overturned.

Rose was allowed to participate in a ceremony honoring MLB’s All-Century Team in 1999, but the league was selective about other moments that he would be allowed to appear at the ballparks in Cincinnati and Philadelphia. — Reuters

Pivotal Game 2

The Liberty were not unaware of the disconnect between their WNBA-leading regular season record and their status as underdogs in their semifinal round series against the Aces. Not that they expected to be deemed favorites, never mind the fact that they won over their archrivals in all three of their previous matches this year. After all, they did wind up bridesmaids versus the defending champions in the 2023 Finals. And in view of the outcome, they acknowledged that they needed to prove themselves first before earning the respect they sought.

Creditably, the Liberty knew well enough to turn their failure into motivation. It was what propelled them to run roughshod over the league heading into Game One of the best-of-five affair the other day. It was also what they figured would give them the edge against the Aces, especially at Barclays Center in front of 14,015 fans looking for vindication. And, as things turned out, they were on the mark in their assessment. They never trailed en route to a double-digit victory, and, if nothing else, they underscored the superior depth of their roster as the difference maker.

Make no mistake. The Big Three of Breanna Stewart, Sabrina Ionescu, and Jonquel Jones performed to expectations, enabling the Liberty to hold the Aces at bay. The latter did manufacture runs, as was expected from noted winners led by newly minted Most Valuable Player A’ja Wilson. Still, none spelled danger for them because they were ready with a counter at every turn, because they brandished unshakable confidence, and because they truly believed they were better than the competition.

Today, the Liberty will need to consolidate their advantage with another triumph. Needless to say, Game Two will be pivotal to their title chances. Win anew, and they have the Aces backpedaling amid the pressure of sweeping the remainder of the series. Which is why they’ll be at their best in Game Two. The opportunity is in their hands, and they aim to make the most of it.

 

Anthony L. Cuaycong has been writing Courtside since BusinessWorld introduced a Sports section in 1994. He is a consultant on strategic planning, operations and human resources management, corporate communications, and business development.

Israeli military begins ground invasion of Southern Lebanon

SMOKE rises over Beirut’s southern suburbs after a strike, amid ongoing hostilities between Hezbollah and Israeli forces, as seen from Sin El Fil, Lebanon, Oct. 1, 2024. — REUTERS

BEIRUT — Israel’s widely expected ground invasion of Lebanon appeared to be getting underway early on Tuesday as its military said troops had begun “limited” raids against Hezbollah targets in the border area.

The military said in a statement that it had begun “limited, localized, and targeted ground raids based on precise intelligence” against Hezbollah in southern Lebanon villages close to the border that posed “an immediate threat to Israeli communities in northern Israel”.

It said the air force and artillery were supporting the ground forces with “precise strikes.”

Local residents in the Lebanese border town of Aita al-Shaab reported heavy shelling and the sound of helicopters and drones overhead. Flares were repeatedly launched over the Lebanese border town of Rmeish, lighting up the night sky.

On Monday, Israeli Defense Minister Yoav Gallant had told local council heads in northern Israel that the next phase of the war along Lebanon’s southern border would begin soon, and would support the aim of bringing home Israelis who have fled Hezbollah rockets during nearly a year of border warfare.

The ground invasion represents an escalating conflict in the Middle East between Israel and Iran-backed militants, sparked by an assault on Israel by Palestinian militant group Hamas on Oct. 7, 2023, that now threatens to suck in the US and Iran.

An Israeli strike in Lebanon early on Tuesday targeted Mounir Maqdah, commander of the Lebanese branch of the Palestinian Fatah movement’s military wing, the Al-Aqsa Martyrs Brigade, according to two Palestinian security officials.

His fate was unknown.

The strike hit a building in the crowded Ain al-Hilweh Palestinian refugee camp near the southern city of Sidon, the sources said. It marked the first strike on the camp, Lebanon’s largest Palestinian camp, since cross-border hostilities between Hezbollah and Israel broke out nearly a year ago.

In Syria, three civilians were killed and nine others injured in an Israeli airstrike on the capital Damascus, Syrian state media said on Tuesday citing a military source. Israel’s military said it does not comment on foreign media reports.

Israel has been carrying out strikes against Iran-linked targets in Syria for years but has ramped up raids since the Hamas attack on Israel’s southern territory on Oct. 7, 2023.

Hamas killed 1,200 people and took about 250 hostage in its assault on Israel, according to Israeli tallies. Israel in response launched a massive assault on Hamas in Gaza, reducing most of the Palestinian territory to rubble, displacing most of its 2.3 million people and killing more than 41,300 Palestinians, according to the Gaza health ministry.

STRIKES ON BEIRUT
Israel’s ground invasion into Lebanon follows its deadly detonation of booby-trapped Hezbollah pagers, two weeks of airstrikes, and its killing on Friday of Hezbollah head Hassan Nasrallah, which dealt the group one of the heaviest blows in decades.

The intensive air strikes have eliminated several Hezbollah commanders but also killed about 1,000 civilians and forced one million to flee their homes, according to the Lebanese government.

Overnight, strikes hit Beirut’s southern suburbs, a security source said. A Reuters reporter witnessed a flash of light and a series of loud blasts about an hour after the Israeli military warned residents to evacuate areas near buildings it said contained Hezbollah infrastructure south of the Lebanese capital.

In the past 24 hours, at least 95 people had been killed and 172 wounded in Israeli strikes on Lebanon’s southern regions, the eastern Bekaa Valley, and Beirut, Lebanon’s health ministry said early on Tuesday.

Hezbollah’s deputy leader Naim Qassem, in a first public speech on Monday since Nasrallah’s death, said that “the resistance forces are ready for a ground engagement.”

He said Hezbollah had continued to fire rockets as deep as 150 km (93 miles) into Israeli territory.

“We know that the battle may be long. We will win as we won in the liberation of 2006,” he said, referring to the last big conflict between the two foes.

Late on Monday, Lebanese troops pulled back about five kilometers (3 miles) from positions along Lebanon’s southern border with Israel, a Lebanese security source told Reuters. A Lebanese army spokesperson did not confirm or deny the movement.

Lebanon’s army has historically stayed on the sidelines of major conflicts with Israel, and in the last year of hostilities has not fired on the Israeli military.

The White House and the US State department did not immediately respond to a request for comment on Israel’s ground operations in Lebanon.

But on Monday, US President Joseph R. Biden had called for a ceasefire.

“I’m more worried than you might know and I’m comfortable with them stopping,” Mr. Biden told reporters when asked if he was comfortable with Israeli plans for a cross-border incursion. “We should have a ceasefire now.”

Israel last week rejected a proposal by the US and France calling for a 21-day ceasefire on the Lebanon border to give time for a diplomatic settlement that would allow displaced civilians on both sides to return home. — Reuters

Taiwan warns of possible storm surge from powerful Typhoon Krathon

REUTERS

KAOHSIUNG, Taiwan — Taiwan mobilized nearly 40,000 troops on Tuesday to bolster rescue efforts as the powerful Typhoon Krathon approaching its populous southwest coast is expected to bring a storm surge and the coast guard raced to locate 19 sailors who abandoned ship.

Taiwan regularly gets hit by typhoons but they generally land along the mountainous and sparsely populated east coast facing the Pacific, but this one will make landfall on the island’s flat western plain.

Krathon is forecast to hit the major port city of Kaohsiung early on Wednesday afternoon, then work its way across the center of Taiwan heading northeast and cross out into the East China Sea, the Central Weather Administration (CWA) said.

Kaohsiung, home to some 2.7 million people, declared a holiday and told people to stay at home as Krathon — labeled a super typhoon by the US Navy’s Joint Typhoon Warning Center — approached.

Li Meng-hsiang, a forecaster for Taiwan’s Central Weather Administration, said the storm has reached its maximum intensity and could weaken slightly as it moves closer to Taiwan, warning of gusts of more than 150 kph (93 mph) for the southwest.

“The storm surge might bring tides inland,” Li said. “If it’s raining heavily it will make it difficult to discharge waters and as a result coastal areas will be subject to flooding.”

Kaohsiung Mayor Chen Chi-mai, speaking to reporters after a disaster management meeting, said the strength and path of the storm were both on par with 1977’s Typhoon Thelma which killed 37 people and devastated the city.

“After the typhoon, the whole of Kaohsiung was without water and electricity, just like a war,” Chen said, recalling the decades-ago destruction. “As much as possible, limit going out.”

Taiwan’s Defense ministry said it had put more than 38,000 troops on standby, as Kaohsiung residents made their own preparations.

“It’s going to strike us directly. We must be fully prepared,” said fisherman Chen Ming-huang. “In the worst-case scenario the ropes might snap and my boat could drift away.”

TSMC, the world’s largest contract chip maker and a major supplier to Apple and Nvidia, said it had activated routine typhoon preparations and did not expect a significant impact to its operations.

SEARCH FOR SAILORS
Off the southeast coast, Taiwan’s coast guard dispatched a boat to rescue 19 sailors from the cargo vessel Blue Lagoon who were forced to abandon ship as it took on water in its engine room, with a rescue helicopter having to turn back due to the wind and rain.

The coast guard said the crew consisted of seven Ukrainians, nine Egyptians and three Russians, which had set off from China’s Caofeidian port for Singapore.

The transport ministry said 85 domestic flights and nine international ones had been canceled for Wednesday, with boats to outlying islands also stopped.

The rail line connecting southern to eastern Taiwan was closed, though the north-south high-speed line was operating as normal, albeit with enhanced safety checks for wind and debris.

In Kaohsiung, most shops and restaurants pulled down their doors and shutters, and traditional wet markets shut with streets mostly deserted.

At a building in Siaogang district, home to the city’s airport, residents practiced how to rapidly set up metal barriers to stop water flooding into the underground parking lot.

“We will have only a few minutes to react if the flooding is coming,” said Chiu Yun-ping, deputy head of the building’s residents’ committee.

Chen Mei-ling, who lives near the harbor, said in past typhoons high tides reached just a few meters (feet) from her house’s main door and she had made preparations.

“We’ve got torches and emergency food supplies,” Chen said. “It’s a strong typhoon and we are worried.” — Reuters

Shigeru Ishiba confirmed as Japan’s prime minister

JAPANESE PRIME MINISTER SHIGERU ISHIBA — REUTERS FILE PHOTO

TOKYO — Shigeru Ishiba was confirmed as Japan’s next prime minister by parliament on Tuesday, paving the way for him to officially unveil his Cabinet as he seeks to heal party divisions and prepare for an Oct. 27 snap election.

The 67-year-old former defence minister won a close-fought contest last week to lead the ruling Liberal Democratic Party (LDP). Mr. Ishiba is expected to hold a late press conference on Tuesday after the Emperor formally appoints him, and his Cabinet, in a ceremony at Tokyo’s Imperial Palace.

Now in power, he must quell simmering anger over rising living costs and his scandal-plagued party, and navigate a volatile security environment in East Asia fueled by an increasingly assertive China and nuclear-armed North Korea.

The veteran lawmaker, seen as somewhat of a party outsider who failed at four previous leadership bids, has already begun picking government and party officials who will contest the upcoming general election with him.

So far those include two rival candidates in the leadership race, Katsunobu Kato as Finance minister and Yoshimasa Hayashi to stay on as chief Cabinet secretary, a pivotal post that includes the role of top government spokesman, two sources familiar with the appointments told Reuters earlier.

A close Ishiba ally, Takeshi Iwaya, a former Defense chief, will take over as foreign minister, while Gen Nakatani will return to the Defense ministry, a position he held in 2016, said the sources, who asked not to be identified because they are not authorized to speak publicly, confirming earlier media reports.

Yoji Muto, a former junior minister, will take charge at the economy, trade and industry ministry, a separate source said.

The Ishiba administration’s approach to diplomacy with Japan’s closest ally, the United States, will be in focus, as he has repeatedly called for a more balanced relationship with Washington.

He has also proposed creating an Asian version of the collective security group North Atlantic Treaty Organization to deter China, an idea that could draw ire from Beijing and has already been dismissed by a senior US official as hasty.

In his victory speech on Friday, he spoke about the need to beef up Japan’s security after recent territorial incursions by Chinese and Russian military vessels.

ECONOMIC POLICY
Mr. Kato’s appointment to the finance ministry will be closely watched given he served in key positions in former premier Shinzo Abe’s administration, which pursued expansionary fiscal and monetary policies.

The Nikkei stock index .N225 fell nearly 5% on Monday in reaction to a surging yen following Ishiba’s win over Sanae Takaichi, a monetary dove and fiscal expansionist, in Friday’s leadership contest. The index recovered ground on Tuesday.

Ms. Takaichi, a hardline conservative he beat by 215 votes to 194 on Friday in the closest leadership election in almost seven decades, appears to not be in the running for a top position after local media reported she declined a senior party post.

That could make it difficult for Mr. Ishiba, a perennial favorite in public opinion polls, to manage a fractious ruling group roiled by scandals.

But despite its troubles, the party which has ruled Japan for most of the postwar era remains likely to hold on to power in the upcoming election given Japan’s weak opposition.

A third of respondents to a weekend poll by the Mainichi newspaper said they supported the LDP, versus 15% for the main opposition Constitutional Democratic Party of Japan.

More than half of the respondents, including those who supported opposition parties, said they were optimistic about Ishiba’s appointment. — Reuters

Chinese military conducts patrols in parts of South China Sea, state media reports

PIXABAY

BEIJING — The Chinese military conducted combat readiness patrols in parts of the South China Sea from Monday to Tuesday, Chinese state media reported, in an extension of rare military drills and exercises in the region over the weekend.

The Southern Theater Command of the Chinese People’s Liberation Army (PLA) conducted combat readiness patrols in efforts to improve combat capabilities and maintain peace and stability in the South China Sea region, according to state media reports.

China claims almost the entire South China Sea despite overlapping claims in the busy waterway by Brunei, Malaysia, the Philippines and Vietnam. In 2016 the Permanent Court of Arbitration in the Hague ruled that China’s claims were not supported by international law, a decision that Beijing rejects.

On Saturday, Chinese air and naval forces conducted maneuvers near the disputed Scarborough shoal after Australia and the Philippines said their militaries would hold joint maritime activities with Japan, New Zealand and the United States in the Exclusive Economic Zone (EEZ) of the Philippines.

The shoal, about 200 km (124 miles) west of the main Philippine island of Luzon and within the Philippine EEZ, has long been claimed by both Beijing and Manila.

In recent talks with China’s top diplomat Wang Yi in New York, US Secretary of State Antony Blinken raised China’s “dangerous and destabilizing actions” in the South China Sea.

Mr. Blinken had previously accused Beijing of aggressive deployments in the South China Sea of its coast guard and fishing vessels suspected of being a maritime militia. — Reuters

Indian textile baron duped with fake Supreme Court hearing, document shows

SUCCO-PIXABAY

NEW DELHI — Indian police are investigating an elaborate scam that swindled a prominent businessman out of $830,000 by summoning him to a fake online hearing before India’s Supreme Court and making a threat of jail which caused him to transfer the funds.

While digital and online frauds are increasingly common in India, a police official in northern state of Punjab told Reuters on Monday that duping someone by holding a purported Supreme Court session was unheard of.

Details of the case emerged after police said on Sunday they arrested two people on the complaint of S.P. Oswal, the 82-year-old chairman of India’s Vardhman Group.

Mr. Oswal said fraudsters posing as federal investigators approached him as a suspect in a money laundering case. They also organized an online court hearing where someone impersonated India’s Chief Justice D.Y. Chandrachud and then he was ordered to deposit his funds in an account as part of the investigation.

“They made a Skype call regarding the court hearing… as per a Supreme Court order I was directed to release all my funds to into a secret supervision account,” Mr. Oswal told police authorities, according to a case document Reuters reviewed on Monday.

The Supreme Court’s registrar and Mr. Chandrachud’s office did not respond to Reuters queries. Oswal also did not respond.

Police on Monday said they had recovered $600,000 from the accused, saying it was considered to be India’s largest recovery so far in such cases.

Oswal’s case documents said he was threatened with a so-called digital arrest, a rising trend in India where scammers interrogate people on video calls and blackmail them into making payments for violations of the law that they never committed.

India’s government in May warned the public that a rising number of cases of “digital arrests” were being reported where cyber criminals sometimes wear police uniforms and pose as law enforcement officers from studios modeled on police stations or government offices. More than 1,000 Skype IDs involved in such activities had been blocked.

Mr. Oswal is one of the most high-profile figures to have been embroiled in such a scam. He leads a five-decade-old textile company which has a turnover of $1.1 billion and a presence in more than 75 countries. — Reuters

Medical firm pauses trial for lupus treatment after patient deaths in Philippines, Argentina

STOCK PHOTO | Image by Silas Camargo Silão from Pixabay

KEZAR Life Sciences said on Monday it has paused a trial of its experimental drug for lupus to review safety data after four patients died in the mid-stage study.

The San Francisco-based company said it had informed the US Food and Drug Administration and European regulators of the decision to pause enrollment and dosing in the trial.

An independent study committee had recommended the pause after reviewing safety data, following the deaths of patients enrolled in trials in the Philippines and Argentina.

Review of the data by the committee showed three of the fatalities showed a common pattern of symptoms and the deaths happened close to the time of dosing, while a non-fatal adverse event showed a similar proximity to dosing, the company said.

Kezar was testing the treatment, zetomipzomib, in patients with active lupus nephritis, a type of kidney disease caused by lupus — where the body’s immune system attacks its own cells and organs.

To date, 84 patients have been enrolled in the mid-stage trial, according to Kezar.

The company said it has not observed any instances of death or serious infections in prior clinical studies of zetomipzomib.

Another mid-stage trail testing zetomipzomib in patients with autoimmune hepatitis, remains active with no serious adverse events observed to date, the drug developer said. — Reuters

East Coast dockworkers strike, in blow to shipping imports and exports

IMAGE VIA THE PORT OF LOS ANGELES

NEW YORK — Dockworkers along the U.S. East Coast and Gulf Coast began a strike on Tuesday, halting the flow of about half the nation’s ocean shipping after negotiations for a new labor contract broke down over wages.

The strike blocks everything from food to automobile shipments across dozens of ports from Maine to Texas, in a disruption analysts warned will cost the economy billions of dollars a day, threaten jobs, and stoke inflation.

The International Longshoremen’s Association (ILA) union representing 45,000 port workers had been negotiating with the United States Maritime Alliance (USMX) employer group for a new six-year contract ahead of a midnight Sept. 30 deadline.

“As a result of the expiration of the master agreement between United States Maritime Alliance (USMX) and the International Longshoremen’s Association (ILA), there is a work stoppage at The Port of Virginia and other ports along the U.S. East and Gulf coasts,” the Virginia port authority said, announcing the stoppage.

The USMX and union did not immediately respond to requests for comment.

But the ILA’s fiery leader, Harold Daggett, said earlier employers like container ship operator Maersk and its APM Terminals North America had not offered appropriate wage increases or agreed to demands to stop port automation projects. The USMX said in a statement on Monday it had offered to hike wages by nearly 50%.

The ILA said in statements on Sunday and Monday that a port strike would go ahead, starting on Tuesday at 12:01 a.m. ET.

The strike, the ILA’s first since 1977, is worrying businesses across the economy that rely on ocean shipping to export their wares or secure crucial imports. The strike affects 36 ports that handle a range of containerized goods from bananas to clothing to cars.

The union is “holding the entire country over a barrel,” said Steve Hughes, CEO of HCS International, which specializes in automotive sourcing and shipping. “I’m really afraid that it is going to be ugly.”

The dispute is also wedging labor-friendly U.S. President Joe Biden into a virtual no-win position as Vice President Kamala Harris runs a razor-tight election race against Republican former President Donald Trump.

Biden administration officials had met with both USMX and ILA ahead of the strike to encourage a deal. But Biden’s administration has repeatedly ruled out the use of federal powers to break a strike in the event of an impasse.

U.S. Chamber of Commerce President Suzanne Clark urged Biden on Monday to reconsider, saying it “would be unconscionable to allow a contract dispute to inflict such a shock to our economy.”

Retailers accounting for about half of all container shipping volume have been busily implementing backup plans as they head into their all-important winter holiday sales season.

Many of the big players rushed in Halloween and Christmas merchandise early to avoid any strike-related disruptions, incurring extra costs to ship and store those goods.

Retail behemoth Walmart, the largest U.S. container shipper, and membership warehouse club operator Costco say they are doing everything they can to mitigate any impact.

New York Governor Kathy Hochul said on Monday the state expects no immediate impact on food suppliers or essential goods. — Reuters

Vietnam fishing boat attacked near contested South China Sea islands, media reports

A VIETNAMESE naval soldier stands guard at Thuyen Chai island in the Spratly archipelago, Jan. 17, 2013. — REUTERS

HANOI – At least 10 Vietnamese fishermen have been injured after their boat was attacked by a foreign vessel while fishing near Paracel islands claimed by both China and Vietnam, state media reports said late on Monday.

The attack took place on Sunday, reported Thanh Nien newspaper, citing authorities in the central province of Quang Ngai. The report did not provide a description of the foreign vessel or how the fishing vessel was attacked.

Three of the fishermen had their legs and arms broken from the attack, the report said, citing Nguyen Thanh Bien, the captain of the fishing boat QNg.

The fishing boat with the 10 fishermen aboard departed a port in the province on September 13, the report said.

Vietnamese and Chinese foreign ministries didn’t immediately respond to Reuters’ requests for comment. Vietnamese authorities are investigating the incident, the report added.

The China-controlled Paracel, known as Hoang Sa in Vietnam, are in the South China Sea, a busy global maritime waterway almost all of which is claimed by China. — Reuters